The UK Government has updated shielding guidance for the nation's most vulnerable people.

The change allows more than two million people across England to emerge from their homes for the first time in ten weeks.

Those with cancer, liver disease and severe asthma, who have been self-isolating from the virus for many weeks, were informed by text message.

The Shielded Patients List (SPL) was put in place to help the most vulnerable during the pandemic, but some people have now been informed they are no longer on the list - without being told by their doctors first.

Here's a round-up of key questions surrounding the updated guidance for those shielding from the pandemic.

What is the new guidance?

Under the new guidelines, people shielding are now allowed to venture outdoors once per day, either with members of their household or one person from another household – as long as social distancing and strict hygiene is maintained.

There is no limit to the amount of time they can now spend outdoors, however it is advised that at-risk people avoid crowds or crowded areas (including private gatherings) and strictly avoid contact with others, especially if they are displaying symptoms of the virus such as a continuous cough or fever.

Who does the guidance apply to?

The shielding guidance applies to anyone who is considered clinically extremely vulnerable, as well as their family, friends and carers.

This includes organ transplant recipients, people with specific cancers and people on immunosuppression therapies as well as those in long-term care facilities for the elderly or with special needs.

There are believed to be 2.2 million at-risk people who were shielding in England.

What is the science behind the updated guidance?

The Government said the change in guidance stems from the substantially lower level of Covid-19 transmission in the country compared to when the lockdown was first introduced.

However a number of charities have called for the Government to be more specific in their scientific basis for updating the guidelines, citing “confusion” caused by the sudden announcement.

“The way it has announced this on a Saturday night, with no warning or consultation with charities and clinicians, has created confusion,” said Gemma Peters, chief executive of Blood Cancer UK. “Until we get (clarity), we advise people to speak to their healthcare teams before making any changes.”

When will the guidance be updated next?

The next review of shielding measures is scheduled to take place in the week beginning June 15, with regular reviews taking place alongside the review of social distancing measures for the wider population.

Communities Secretary Robert Jenrick flagged on Sunday that guidance for those shielding could become strict again if the virus starts to flare up, but added that he is hopeful of future guidance being more tailored to each individual, rather than the current blanket approach.

What about the rest of the UK?

The updated guidance only applies to England, but Scotland, Wales and Northern Ireland are believed to each be in the process of regularly reviewing their shielding guidelines.

According to Mr Jenrick, Scotland, Wales and Northern Ireland “will issue their own guidance in due course”.